Honkai Star Rail Zandar (Lygus) Boss Guide

Honkai Star Rail 3.5 mission has dropped and it features one of the hardest bosses in the game. The boss is no other than ‘First Genius, Entelechy, Zandar’ AKA Lygus. The Zandar (or Lygus) boss fight is very challenging and players are likely to struggle against him. So, here is a guide on how to defeat Zandar in Honkai Star Rail. This guide features a detailed explanation of Zandar’s move sets, the best characters against him, and how you can counter his abilities.

HSR Zandar Boss Fight Mechanics Explained

First Genius, Entelechy, Zandar Boss Guide Honkai Star Rail
Image Credit: Hoyoverse/Honkai Star Rail (screenshot by Sanmay/ Beebom)

Lygus has finally revealed his true identity, revealing himself to be one of the nine vessels of Zandar One Kuwabara. His big reveal also accompanies a massive boss fight against him.

First Genius, Entelechy, Zandar is a complicated boss in Honkai Star Rail. He has multiple different moves that must be understood correctly in order to win against him. Here is a quick explanation of all Zandar’s moves in Honkai Star Rail:

Move NameExplanation
Summon and HealZandar can summon mythical enemies and heal them during his turn.
Mode ChangeZandar can change his modes and he takes increased damage whenever he changes his modes.
Evolution ModeThis is Zandar’s base mode. Summoning Memosprites or having more enemies on the field will make Zandar change his mode faster. Having 4 or more new allies or enemies will change the mode to Disputation.
Antinomy StateRecharges Ultimate for a random ally and makes them take immediate action. If the Ultimate ability triggered by this effect is used, then the ally take damage equal to 50% of their Max HP. Shield effects can block this damage and it is Non-Fatal.
Disputation ModeZander starts to prepare his Ultimate attack, while also taking increased damage. Defeating 10 enemies will change this mode back to Evolution. However, Zandar will use his Ultimate ability before he changes his mode.
Query: Prime Mover’s OutcomeThis is Zandar’s ultimate ability. It deals massive AoE damage and inflicts Entanglement. The damage and number of allies being inflicted with Entanglement increases with each turn of Zandar in his Disputation mode.

How to Defeat Lygus AKA Zandar Boss in Honkai Star Rail

Honkai Star Rail Zandar (Lygus) Boss Guide
Image Credit: Hoyoverse/Honkai Star Rail (screenshot by Sanmay/ Beebom)

Now that you learned about Zandar’s move, you are one step closer to defeating him. To defeat Zander in Honkai Star Rail, you first need to choose the correct characters for the fight. Next, you have to correctly understand and counter his mechanics. The following sections will guide you on which characters to pick and how to counter his abilities.

Best Characters for Zandar Boss Fight

Best Characters against Zandar boss in Honkai Star Rail
Image Credit: Hoyoverse/Honkai Star Rail (screenshot by Sanmay/ Beebom)

Zandar changes his mode quickly based on the number of enemies and the number of ally memosprites spawned during the fight. This means that fighting Zandar with a Remembrance character can be very difficult. Other than that, you need to pick character that deal Physical, Ice or Wind damage to him. Here are the best characters for the Zandar boss fight:

DPSSupportSustain
HysilensRuan MeiLingsha
PhainonRobinAventurine
The HertaTribbieGallagher
BladeJadeNatasha
ArgentiPelaFu Xuan
JingliuBronyaGeopard
Black SwanSundayHuohuo
SaberTingyun

The best teams for taking down Zandar in Honkai Star Rail are:

  • The Herta Hypercarry: The Herta, Jade, Ruan Mei, Lingsha
  • Phainon Hypercarry: Phainon, Sunday, Bronya, Tingyun
  • Argenti Hypercarry: Argenti, Jade, Ruan Mei, Lingsha
  • Hysilens Stacked DoT: Hysilens, Kafka, Black Swan, Gallagher

Picking any of these teams should let you easily defeat Zandar in Honkai Star Rail, as long as you make sure to counter his abilities as mentioned below.

Counter Zandar’s Boss Mechanics in HSR

Zandar boss mechanic Antimony State HSR
Image Credit: Hoyoverse/Honkai Star Rail (screenshot by Sanmay/ Beebom)
  • First, you should never use the Ultimate triggered from the Antinomy State effect, unless the targeted ally is Phainon. For every other character, the massive HP reduction is simply not worth it.
  • Next, defeat his summoned enemies as quickly as possible during his Disputation Mode. This will greatly reduce the damage from his Ultimate ability.
  • Finally, avoid using characters with Memosprites. If you must use them, keep it only at one character.

That’s all you need to do to defeat First Genius, Entelechy, Zandar in Honkai Star Rail. Have any questions related to this boss guide? Ask us in the comment section below.

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